Perform a clean boot following steps below that fix the mosue problem if third party app conflict causing the issue. Sometimes third party software conflict with windows can cause this mouse scroll problem. Is the mouse scrolling not working on a specific program? open different applications or programs and check if the mouse scrolling working as expected.If you have a wireless mouse then check with replacing its battery, because sometimes the scroll wheel behaves erratically once the battery is almost out.Disconnect and reconnect the mouse to the different USB port.Before applying any troubleshooting steps first reboot your PC, This will fix the mouse scrolling problem if a temporary glitch causing the problem.